Monthly Archives: June 2010

Hidden Cause #1 Why You Still Have Low Thyroid Symptoms

Hidden Cause of Low Thyroid SymptomsToday I’m  starting a new series called,

“Why You Still Have Low Thyroid Symptoms When Your Labs Are Normal”

There are millions of women walking around right now that have low thyroid symptoms.The number one cause of low thyroid in America is an autoimmune attack called Hashimoto’s Thyroiditis— but I’m not going to talk about that.   I’m going to reveal one of the other 23 reasons why you still suffer with low thyroid symptoms.

The first hidden cause of your thyroid symptoms is Central Nervous System Serotonin Deficiency.

“What? Serotonin has something to do with thyroid function?”

Yes, it does, and it’s complex but I’m going to  reveal the major players.

There’s a place in your brain called the hypothalamus.  In the hypothalamus is a region called the  periventricular nucleus (PVN.)

This brain area is critical for your suffering with thyroid symptoms (even though your thyroid labs look normal and you’re taking thyroid hormones.)

Levels of Serotonin in your Central Nervous System (brain and spinal cord) influence the PVN.

Low levels of Serotonin make you have low-thyroid stimulating hormone (TSH).

I’m not going to get into the pathways more than that.  I’m telling you about the Serotonin-PVN-TSH-Connection because I would be shocked if any of your “thyroid” doctors know one iota about this important circuit and how it could help end your suffering.

See, taking thyroid hormones for this problem– this serotonin problem– is not going to help your low thyroid symptoms.

Your labs will look “normal” and pretty soon your doctor is going to drop the “D” word on you…depressed.

He/she will say…”Maybe you need to just go ahead and take an anti-depressant.” NO! The extra-confusing  thing is when you take the anti-depressant, you might actually feel better —but not because you were depressed. You might feel better because some anti-depressants will temporarily increase the activity of Serotonin in the brain! But taking the anti-depressants will fail to make you symptoms go away.

The biggest influence on Serotonin is your blood sugar.

Blood sugar regulation is the one thing that determines how well you will make serotonin in your brain.

So that means you need to have regular, steady glucose, not up and down glucose. Low blood sugar (hypoglycemai) is bad for your thyroid. High blood sugar is bad for your thyroid..

Unstable blood sugar levels cause unstable Serotonin levels that can cause LOW Thyroid Stimulating Hormone…

…And you end up with thyroid symptoms like these:

  • Tired, sluggish
  • Can’t lose weight even with exercise
  • Feel cold—hands, feet, or all over
  • Require excessive amounts of sleep to function properly
  • Increase in weight gain even with low-calorie diet
  • Gain weight easily
  • Difficult, infrequent bowel movement
  • Depression, lack of motivation
  • Morning headaches that wear off as the day progresses
  • Outer third of eyebrow thins
  • Thinning of hair on scalp, face or genitals or hair loss
  • Dryness of skin and/or scalp
  • Mental sluggishness
  • Nervousness and emotional
  • Insomnia
  • Night sweats

You can have any or all of these symptom, even though your lab numbers are “normal.”

This Serotonin-Thyroid connection is real science. This is evidence based medicine.

Sidebar: “Evidenced-based medicine”, by the way, is really prejudiced-based medicine because if your evidence isn’t drug-based evidence then the establishment doesn’t believe you.  Well, they can believe the Serotonin Connection because it comes straight out of scientific research.

So that’s hidden cause #1….and one reason why you can still be having thyroid symptoms even though your labs look normal.

I hop you use this important information and can get plucked out of the jungle of thyroid hormone disorders, because my goodness, they are mismanaged and misunderstood.

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Hidden Cause #3 Why You Still Have Low Thyroid Symptoms

Today I reveal  “Hidden Cause Number 3 Why You Still Have Thyroid Symptoms”, even though your labs look normal…and even though you’re taking thyroid hormones.

The third hidden cause of Low Thyroid Symptoms is high levels of cytokines.

Cytokines are messengers that your immune system uses as part of the inflammation process.

Women that have inflammatory conditions such as arthritis, inflammatory bowel conditions, asthma…or autoimmune conditions like Lupus or RA…usally have high levels of cytokines.

High cytokine levels depress and squash the circuit in your brain that helps you make thyroid  hormones.

Cytokines may not squash this circuit so much that your TSH is low according to  “normal reference range.” But remember, the lab ranges that are used to measure TSH and T4, are too WIDE. Too forgiving.

In my office, I use a “functional” range.  It’s a narrow range.  The power of the functional range is that every day I discover  “hidden” thyroid dysfunction using this “functional” narrow range.

“How do you know if I have elevated cytokines?”

Well, these cytokines have names like interleukin 2, interleukin 4, tumor necrosis factor alpha.  You can easily test for these.  These are blood tests.  In fact, these are some of the same  tests that I do for my Multiple Sclerosis, Lupus and RA  patients to find out about exactly how their immune system has become unbalanced.

I do the same deep analysis for the women who have thyroid hormone problems….the women that come in suffering with thyroid symptoms but “mysteriously” their labs are “normal.”

Thousands of women are wandering through life lost, feeling awful, without hope because their thyroid problem is mis-diagnosed and mis-managed.

They feel horrible…they have fatigue, depression, they can’t lose weight. It’s cruel, but they gain weight very rapidly. Ttheir hair is brittle, their nails are brittle, a lot of them are depressed.

But the doctors are telling them, “Well, I just don’t see a reason why you still feel bad.  Maybe I’ll up your prescription–or maybe I just need to give you an anti-depressant.” 

Giving antidepressants to these women is  WRONG.

There are over 24 different ways that your thyroid hormones can go wrong. (24!) And the third way, is when cytokines  get high enough to  put their foot down on that normal circuit that helps you make thyroid hormones.

The next question that must be is… “What’s causing the inflammation?” At the Center for Low Thyroid Solutions I answer this question using a comprehensive analysis.

I use sophisticated lab tests to investigate:

  • Food sensitivities/ intolerance (I use the most sensitive test available)
  • Gastrointestinal infections (totally hidden 80% of the time)
  • Parasites
  • Viral infections
  • Vitamin D deficiency (some women have a genetic problem called a Vitamin D Receptor Polymorphism)

What I’m telling you is that you can’t just accept the fact that your doctor says,

“Your labs are normal; you’re taking thyroid hormones; you still feel bad?; I guess maybe you’re just depressed. Try this antidepressant drug.”

Don’t buy that load of junk!  Do not settle for a life where you feel horrible.

You have to find the right doctor that knows how to assess comprehensively… and knows about these different factors I just told you about (There all in the scientific literature.).

Here’s the giant roadblock in your way….,a scary large number of doctors don’t read.  Even the so-called “number one” endocrinologist in your city– many of them don’t read.

What I do is not their approach.  They do not take a functional approach.  They’re looking just at the lab ranges and if the lab numbers are okay, you’re okay.

Ridiculous isn’t it? These doctors have forgotten how to think.

Today I’ve shared with you how cytokine elevations can cause low thyroid symptoms.  You can test for these with simple but specialized blood tests.

Do NOT settle. You don’t have to suffer.

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© 2010 Dr. David Clark

Hidden Cause #2 Why You Still Have Low Thyroid Symptoms

Today I’m going to reveal hidden cause number two, why you still have thyroid symptoms.

This series is designed to do is to help open your eyes so that you can understand why you still are suffering with symptoms like fatigue and hair loss, low libido, feeling cold….understand why you still have those symptoms even though you’re taking thyroid hormones…. or even though your thyroid numbers look normal.

And hidden cause number two why you’re still suffering is because of a neurotransmitter called Dopamine.

Now I’m going to keep this science really simple…..

Your pituitary, which is a very small gland in your brain, makes thyroid stimulating hormone – TSH.

I’m sure you probably heard of that because that’s probably the only thing your doctor is monitoring, right?

Monitoring TSH is the only thing the status quo medical model does when it comes to thyroid hormone problems.

Pretty much no matter what the doctor thinks your problem might be (and they really only think it’s about one of two things) you get prescribed thyroid hormones.

The doctor doesn’t actually manage your thyroid problem… the doctor manages your TSH.(!)

So, if your TSH gets too high, well they increase your medication.  If your TSH gets too low, they decrease your medication. (so easy I could teach a 5 year old to do it).

The doctor looks at your TSH levels as the Be-All End-All… that couldn’t be more wrong.

The  thing about thyroid hormone problems that confuses most doctors and endocrinologists is there are  about 24 different ways that your thyroid hormones can go wrong – 24.

And most of your doctors are only testing TSH and total T4 and that’s about it.  That’s going to detect only 1, maybe 2 of the 24 different patterns.

The one I’m revealing to you today is Dopamine.

Your hypothalamus in your brain tells the pituitary to make TSH.

The Dopamine problem and its connection with thyroid works like this...there has to be sufficient Dopamine in your hypothalamus to generate the signal to pituitary to make TSH.

If there’s not enough Dopamine activity in your brain, then your pituitary doesn’t know how to make TSH.

Now, The TSH number on your labs will be within the normal lab range, but outside what I call the functional range.

The functional range is different than the lab’s range, because the lab range is pretty much garbage as a reflection of optimal function. It’s so wide that only the very high and very low get flagged.

…So with this Dopamine problem your TSH looks normal but you have thyroid symptoms—cold, fatigued, depressed, can’t lose weight, hair loss.  You may even be taking thyroid hormones.

“How Do I Know if You Have the Dopamine Problem?”

The clue to the Dopamine problem is  that you have, along with the fatigue and libido problems and the depression and the constipation and the can’t lose weight—along with those thyroid symptoms you have Dopamine symptoms.

The classic symptoms of insufficient Dopamine are:

  • feelings of worthlessness
  • anger and aggression when under stress
  • feelings of hopelessness
  • difficulty paying attention
  • distracted from task
  • inability to finish tasks
  • self-destructive thoughts


  1. If you’re suffering with those Dopamine symptoms
  2. AND you’re suffering with those thyroid symptoms
  3. BUT your TSH looks normal
  4. AND you’re taking thyroid hormone…

Then there’s a really good chance that Dopamine is why you still have a thyroid problem.

This Dopamine problem can be helped with special diet modification, lifestyle changes and specific supplementation.

Blood sugar control is probably the biggest thing to look at because Dopamine synthesis is  linked with blood sugar fluctuations.

ALERT: I don’t want you to fall victim to  the idea that you can test central nervous system neurotransmitter levels with urine testing.  That’s not valid at all.

I use an extensive questionnaire that helps me pinpoint specifically if you do actually have those Dopamine problems.

If you do, then I have to start digging into WHY do you have those Dopamine problems–this takes some detective work.  That’s what a good doctor will do.

If you’re suffering with thyroid hormone symptoms AND those Dopamine symptoms, dopamin can be the reason why you are still suffering, even though your labs look normal.

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© 2010 Dr. David Clark